منابع مشابه
MADIT-II and its implications.
The major risks associated with coronary disease are angina, acute myocardial infarction, reduced cardiac function as manifest by depressed left ventricular ejection fraction and congestive heart failure, and sudden arrhythmogenic cardiac death. During the past three decades, considerable advances have been made in the management of patients with coronary heart disease with betablockers, calciu...
متن کاملMADIT-II: clinical implications.
The MADIT-II trial showed that in patients with a prior myocardial infarction and ejection fraction </=0.30, prophylactic implantation of a defibrillator improves survival with a 31% reduction in mortality during an average follow-up of 20 months. Electrophysiologic inducibility was positive in 36% of patients at the time of ICD implantation. Inducibility was associated with increased ICD utili...
متن کاملMADIT II , Multicenter Automatic Defibrillator Implantation Trial II
Cardiogenic shock (CS) occurs in 5% to 8% of patients hospitalized with ST-elevation myocardial infarction (STEMI). Recent research has suggested that the peripheral vasculature and neurohormonal and cytokine systems play a role in the pathogenesis and persistence of CS. Early revascularization for CS improves survival substantially. New mechanical approaches to treatment are available, and cli...
متن کاملRepolarization variability in the risk stratification of MADIT II patients.
AIMS QT variability has been reported to be associated with ventricular arrhythmias and sudden cardiac death. There is limited data regarding variability in T-wave morphology and its prognostic value. In this study, we present a novel approach for the measurement of T-wave variability (TWV) reflecting changes in T-wave morphology, and we investigate the prognostic significance of Holter-derived...
متن کامل[MADIT II prematurely terminated: major impact on health economics?].
Last November the independent Data and Safety Monitoring Board (DSMB) of the MADIT II trial decided to prematurely terminate the study because a significant improvement in survival had been found in the group of patients receiving an implantable cardio-verter defibrillator (ICD). The MADIT II trial followed an earlier study (MADIT) that already had demonstrated that ICD has a significant benefi...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2003
ISSN: 0195-668X
DOI: 10.1016/s0195-668x(02)00627-9